One of the most revered business leaders of the country, Mir Nasir Hossain has a diverse range of business interests including construction, real estate, telecom, ICT, Software Development, ceramic tiles manufacturing, Textile, Liquefied Petroleum Gas (LPG), banking and insurance. He excelled as a student and achieved his post-graduation in accounting from the University of Dhaka with distinction. He joined EBL Board in 1993.

Mir Telecom Ltd., a business concern under his dynamic leadership, won the National Export Gold Trophy thrice in 2012-13, 2013-14 & 2016-2017 in Service Sector. He received the export trophy award from the Honorable Prime Minister of the People's Republic of Bangladesh. He was declared a CIP (Commercially Important Person) by the Ministry of Industries for 2012, 2013, 2017 and CIP Export 2014 & 2015 from the Ministry of Commerce for his significant contributions to the industrial growth of the country.

He led the Federation of Bangladesh Chambers of Commerce and Industry (FBCCI), the apex trade organization of the country, as its President from 2005 to 2007, and served the organization prudently with commitment and dedication. He held many important positions in various regional business and trade bodies including Senior Vice President of SAARC Chamber of Commerce and Industry (SCCI) and Vice President of Confederation of Asia Pacific Chambers of Commerce and Industry (CACCI). Currently, he is the President of Faridpur Diabetic Association and Chairman of the Governing Body of Faridpur Diabetic Association Medical College. He is the Chairman of Mir Securities Ltd.

He is the Chairman of both the Executive Committee (EC) and Risk Management Committee (RMC) of the Board of EBL. He also serves as the Chairman of Shariah Supervisory Committee of EBL Islamic Banking.

He is actively engaged in various social works, most notably Bangladesh Red Crescent Society as life time member.